Canalicular adenoma ca is an uncommon but unique benign tumor of salivary gland origin. Monomorphic adenoma definition of monomorphic adenoma by. Salivary gland basal cell and canalicular adenomas archives. Given the usual small biopsies, ihc may be useful in distinguishing canad from other tumors in the differential diagnosis. Despite having an excellent prognosis, the histological diagnosis and.
Canalicular adenoma, salivary glands of springerlink. Aug 21, 2014 there is a lack of a comprehensive immunohistochemical ihc analysis of canalicular adenoma canad, especially when combined with a description of the unique histologic features. All structured data from the file and property namespaces is available under the creative commons cc0 license. Canalicular adenoma ca is an uncommon benign neoplasia of salivary glands which is clinically difficult to recognise. Bilayered strands or ribbons of columnar cells with loose, well vascularized stroma. Well circumscribed, lobulated tumour with well developed fibrous connective tissue capsule.
Canalicular adenoma is a relatively rare benign tumor of the salivary glands, found almost exclusively in the minor salivary glands of the upper lip. The risk of tumor recurrence following surgery is minimal. Their incidence peaks during the seventh decade of life. Cases of basal cell adenomas 14 and canalicular adenomas 11 were retrieved from the surgical pathology files of henry ford hospital, detroit, mich, and the oral pathology files of university of california at san francisco. The canalicular type of monomorphic adenoma is a rare salivary gland tumor that has had infrequent notice in the literature. A 48 yearold female patient was admitted to our clinic, who suffered from asymptomatic right preauricular mass lesion for about 8 months. One hundred three tumors were identified and studied. Canalicular adenoma ca is a benign neoplasia of salivary glands, which although representing less than 1% of salivary gland tumours, is the second or third most common benign tumour of minor salivary glands 1,2.
Canalicular adenoma is an unusual benign epithelial neoplasm of the minor salivary glands located primarily on the upper lip. They account for 1% of all salivary gland neoplasms. Canalicular adenoma is a rare benign salivary gland tumour usually noted in elderly patients. Files are available under licenses specified on their description page. This is a very rare benign neoplasm, that makes up about 1% of all salivary gland tumors, or about 4% of all benign salivary gland tumors. Describe the role of imaging in the evaluation and diagnosis of hepatic adenoma. Canalicular adenoma ca is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Often cystic change, apocrine, mucous or pigmented cells histopathology 1999. Microscopically, ca can be mistaken for a polymorphous lowgrade. Twenty nine cases from the files of the afip are analyzed. It appears as a slowgrowing node, less than 3 cm in diameter, painless. We report a case of canalicular adenoma in the upper labial mucosa of a male patient, highlighting the clinical and histopathological differential peculiarities compared to other lesions of similar location.
Ca is an uncommon benign neoplasm that can develop in minor salivary gland duct tissues throughout the oral cavity. Clinical and histological features of multifocal canalicular. Systematic evaluation of the world health organization classification of salivary gland tumors. Tumors diagnosed as basal cell adenoma, canalicular. Originally thought to be derived from terminal duct origin 1, 2, there has been controversy about origin and separation from other salivary gland neoplasms. It is the third most common benign tumor of minor salivary glands, representing less than 1% of all salivary neoplasms. Immunohistochemical evaluation of 25 salivary gland basal cell and canalicular adenomas. Convert and create pdf from various types of files like word doc, excel xls, powerpoint ppt. Another important entity to be distinguished from canalicular adenoma is adenoid cystic carcinoma. Monomorphic adenoma canalicular type monomorphic adenoma canalicular type nelson, j. Medical university of south carolina, university of kentucky, louisiana state uni versity, and temple university. Despite its benign nature, some patients may present multiple nodules and also microscopic growth that can be multifocal with foci of tumor within the adjacent gland.
Mar 07, 2018 what is the prognosis of a canalicular adenoma of salivary gland. Soft tissue masses mucosa ginigva and alveolar buccal irritation fibroma canalicular adenoma 40 years pleomorphic adenoma adenoma of the parotid gland which was located on the deep lobe of the gland with unusual location the tumor was excised successfully without total parotidectomy. The cells of adenoid cystic carcinomas are similarly small with high nuclear cytoplamic ratio,but nuclei are less regular,hyperchromatic,with a coarsely granular chromatin,and nucleoli are more prominent. Canalicular adenoma type of benign salivary gland tumor occurs most often in minor salivary glands.
Salivary gland basal cell and canalicular adenomas. Mar 01, 2005 canalicular adenomas are benign neoplasms with a unique predilection for the upper lip 80% of cases. Canalicular adenoma definition of canalicular adenoma by. Canalicular adenoma is a benign salivary gland tumour that occurs mainly in elderly patients and has a predilection to occur on the upper lip. The tumor is usually confined to soft tissue and rarely presents with bone erosion.
Canalicular adenoma is a benign, epithelial salivary gland neoplasm arranged in interconnecting cords of columnar cells. Recognize the typical and atypical imaging features of hepatic adenoma. Canalicular adenoma is a rare benign salivary gland tumor of the oral cavity, typically located in the upper lip and buccal mucosa and infrequently found on the palate. Case report multiple bilateral warthins tumors of the.
Seifert and donath 1996 15 basal cell adenoma and canalicular adenoma hybrid tumours seifert and donath 1996 15 warthins tumour and sebaceous adenoma hybrid tumours hosokawa et al. The use of the terms monomorphic adenoma, basal cell adenoma and canalicular adenoma as applied to salivary gland tumors. These tumors have undergone taxonomic drift, with many terms used to describe these tumors over the years table 1. May infiltrate capsule and exhibit extracapsular tumor islands. Canalicular adenoma is a benign neoplasm of the salivary glands. We would like to show you a description here but the site wont allow us. Pleomorphic adenoma chondromyxoid matrix with hyaline and plasma adenocystic carcinoma possible utility of c kit, smaller cells with hyperchromatic nuclei, bilayered tubules presence of plga subtypes papillary cystadecarcinoma higher recurrence and regional metastasis cribiform adenocarcinoma tongue localization and. A case of a large and locallyaggressive palatal canalicular adenoma is presented. Canalicular adenoma canad is an uncommon benign salivary gland neoplasm. In such cases, it is critical to make a definite diagnosis as each of these tumors has an entirely different treatment protocol. Aug 21, 2014 canalicular adenoma canad is an uncommon benign salivary gland neoplasm. Canalicular adenoma is an uncommon salivary neoplasm affecting almost exclusively the minor salivary glands, and representing % of all salivary tumors nelson and jacoway, 1973, batsakis, 1991, furuse et al. Canalicular adenoma ca is a benign epithelial salivary gland neoplasm characterized by chains of columnar epithelial cells arranged in thin anastomosing cords with a beaded pattern and preference for minor salivary glands, most probably originating from excretory duct cells.
Archival pathology material from the files of henry ford hospital, detroit, mich, and the university of california at san francisco. Bhaskar and weinmam cited by gardner were the first who defined and illustrated the tumour that is now referred to as a canalicular adenoma. Outcomesresolutions the prognosis of canalicular adenoma of salivary gland is generally excellent with surgical intervention and complete removal, since it is a benign tumor. Foxit software is the reliable source for fast, affordable, and secure pdf solutions. Other locations arebuccal mucosa, the palate and the parotid gland. Canalicular adenoma composed of columnar epithelial cells arranged in single or double layer forming branching chords. Immunohistochemical pattern of pleomorphic adenoma. Pdf converter is a online webbased document to pdf converter software. Multifocal canalicular adenoma of the minor labial salivary. To report a case of canalicular adenoma ca and discuss the use of immunohistochemistry to better address the diagnosis given some unusual characteristics in this patient. The most common site of occurrence is the upper lip.
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